EC 3.1.3.5 NT5C / NT5E 5 reactions
Enzymes & cofactors
Search by name, gene symbol, EC number or the disorder it causes. Open any enzyme to see every reaction it catalyses, what accelerates it and what inhibits it.
Showing enzymes whose reactions use Pi.
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EC 2.4.2.1 PNP 4 reactions
PNP deficiency: T-cell immunodeficiency
EC 1.2.1.12 GAPDH 3 reactions
EC 3.1.3.9 G6PC / SLC37A4 2 reactions
von Gierke disease (GSD I): fasting hypoglycaemia, lactic acidosis, hyperuricaemia
EC 4.1.1.33 MVD 2 reactions
EC 6.3.4.3 MTHFD1 1 reactions
EC 6.4.1.2 ACACA 1 reactions
Biotin-dependent; inhibited by AMPK; ACC inhibitors studied in NASH/obesity
SLC25A4 / SLC25A3 1 reactions
EC 6.3.4.4 ADSS2 1 reactions
EC 6.3.3.1 GART 1 reactions
EC 2.1.3.2 CAD 1 reactions
EC 2.3.3.8 ACLY 1 reactions
EC 6.3.4.16 CPS1 1 reactions
CPS I deficiency: hyperammonaemia, normal orotic acid
EC 6.3.5.5 CAD 1 reactions
EC 6.3.4.2 CTPS1 1 reactions
EC 7.1.2.2 ATP5 genes 1 reactions
Inhibited by oligomycin; bypassed by uncouplers (DNP, UCP1)
EC 7.1.2.2 ATP5 genes 1 reactions
Inhibited by oligomycin; bypassed by uncouplers (DNP, UCP1)
EC 6.3.5.3 PFAS 1 reactions
EC 3.1.3.11 FBP1 1 reactions
FBPase deficiency: fasting hypoglycaemia, lactic acidosis, ketosis
EC 2.4.1.1 PYGM / PYGL 1 reactions
McArdle disease (GSD V, muscle); Hers disease (GSD VI, liver)