What it does, reaction by reaction
Purine De Novo Synthesis (IMP synthesis through to AMP/GMP) Nucleotide Metabolism · Cytosol
FGAR → formylglycinamidine ribonucleotide (FGAM)
Converts Formylglycinamide ribonucleotide (FGAR) into Formylglycinamidine ribonucleotide (FGAM)
› Notes
FGAM synthetase catalyzes FGAR + glutamine + ATP + H2O → FGAM + glutamate + ADP + Pi. The glutamine-derived nitrogen becomes N3 of the purine ring; ATP activates the formyl group before amidination.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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