EC 3.1.3.5 NT5C / NT5E 5 reactions
Enzymes & cofactors
Search by name, gene symbol, EC number or the disorder it causes. Open any enzyme to see every reaction it catalyses, what accelerates it and what inhibits it.
Showing enzymes whose reactions use H2O.
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EC 2.7.4.6 NME1 / NME2 4 reactions
EC 4.2.1.11 ENO1 / ENO2 / ENO3 3 reactions
EC 3.5.1.6 UPB1 2 reactions
EC 2.3.3.1 CS 2 reactions
Entry step of TCA; inhibited by citrate, ATP, NADH, succinyl-CoA
EC 3.5.4.12 DCTD 2 reactions
EC 3.5.2.2 DPYS 2 reactions
EC 3.1.3.9 G6PC / SLC37A4 2 reactions
von Gierke disease (GSD I): fasting hypoglycaemia, lactic acidosis, hyperuricaemia
EC 3.1.1.34 LPL 2 reactions
LPL or apoC-II deficiency: familial chylomicronaemia (type I), pancreatitis
EC 2.1.2.1 SHMT1 / SHMT2 2 reactions
EC 1.17.3.2 / 1.17.1.4 XDH 2 reactions
Target of allopurinol and febuxostat; deficiency causes xanthinuria
EC 3.1.1.31 PGLS 1 reactions
EC 3.5.4.4 ADA 1 reactions
ADA deficiency: severe combined immunodeficiency (dATP accumulation inhibits RNR)
EC 3.1.1.3 PNPLA2 1 reactions
First and rate-limiting step of adipocyte lipolysis
EC 4.2.1.24 ALAD 1 reactions
Inhibited by lead: lead poisoning with basophilic stippling, elevated ALA
EC 3.5.4.6 AMPD1 1 reactions
EC 3.5.3.1 ARG1 1 reactions
Argininaemia: spastic diplegia, less severe hyperammonaemia
EC 3.5.1.1 ASRGL1 1 reactions
EC 2.3.1.85 FASN 1 reactions
EC 3.2.1.108 LCT 1 reactions