What it does, reaction by reaction
1 reactions
Purine De Novo Synthesis (IMP synthesis through to AMP/GMP) Nucleotide Metabolism · Cytosol
step 6
Irreversible
FGAM → 5-aminoimidazole ribonucleotide (AIR)
Converts Formylglycinamidine ribonucleotide (FGAM) into 5-Aminoimidazole ribonucleotide (AIR)
› Notes
AIR synthetase catalyzes ATP-dependent ring closure: FGAM + ATP → AIR + ADP + Pi. This irreversible cyclization forms the imidazole portion of the purine nucleus.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
Nothing is fetched until you ask, so the page stays fast and the request is yours rather than automatic.
Europe PMC · ten most recent, newest first