unreviewed

Adenine nucleotide translocase (ANT) + phosphate carrier (PiC)

1 reactions · 1 pathways

Cofactors used

What it does, reaction by reaction

1 reactions

Oxidative Phosphorylation (Chemiosmotic Mechanism and ATP Synthase) Energy Metabolism & Cellular Respiration · Inner mitochondrial membrane

step 5 Reversible

ATP export and phosphate import: ATPmatrix + ADPcytosol ⇌ ATPcytosol + ADPmatrix; H2PO4−cytosol + H+intermembrane space → H2PO4−matrix + H+matrix

Converts ATP (matrix) ADP (cytosol) into ATP (cytosol) ADP (matrix) Pi (cytosol) H+ (intermembrane space)

› Notes

Required substrates: ADP, ATP, Pi, and the electrochemical gradient. These transport steps are essential to effective oxidative phosphorylation and are included when estimating the practical ATP cost per cytosolic ATP delivered.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Oxidative Phosphorylation (Chemiosmotic Mechanism and ATP Synthase)

Listed there as: Adenine nucleotide translocase (ANT)

Accelerated by

Cytosolic ADP, matrix ATP, membrane potential

Inhibited by

Atractyloside/carboxyatractyloside; bongkrekic acid

Hormonal control

Indirect modulation through cellular ATP demand and mitochondrial content

Recent literature

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