EC 2.3.1.6 CHAT 1 reactions
Acetylcholine synthesis; AChE is the organophosphate target
Enzymes & cofactors
Search by name, gene symbol, EC number or the disorder it causes. Open any enzyme to see every reaction it catalyses, what accelerates it and what inhibits it.
EC 2.7.1.32 CHKA 1 reactions
EC 7.1.1.2 NDUFA-S subunits 1 reactions
EC 1.3.5.1 SDHA-D 1 reactions
SDH mutations: paraganglioma, phaeochromocytoma, GIST; inhibited by malonate
EC 7.1.1.8 MT-CYB / UQCRC1-2 1 reactions
EC 7.1.1.9 MT-CO1-3 1 reactions
Inhibited by cyanide, carbon monoxide, azide, H2S
1 reactions
EC 2.1.1.6 / 2.1.1.67 COMT/TPMT 1 reactions
TPMT deficiency: azathioprine/6-MP myelosuppression
EC 1.3.3.3 CPOX 1 reactions
EC 6.3.5.5 CAD 1 reactions
EC 6.3.4.2 CTPS1 1 reactions
EC 2.7.7.15 PCYT1A 1 reactions
EC 1.14.99.1 PTGS1/PTGS2 1 reactions
Irreversibly acetylated by aspirin; NSAID and coxib target
1 reactions
EC 4.2.1.22 CBS 1 reactions
Homocystinuria: marfanoid habitus, DOWNWARD lens dislocation, thrombosis; B6-responsive forms
EC 4.4.1.1 CTH 1 reactions
EC 3.5.4.5 CDA 1 reactions
EC 1.14.14.1 CYP genes 1 reactions
CYP3A4 handles ~50% of drugs; major site of drug-drug interactions
EC 2.3.1.9 ACAT2 1 reactions
EC 6.3.4.5 ASS1 1 reactions
Citrullinaemia type I