unreviewed
CYP8B1, CYP27A1 and side-chain oxidation enzymes
1 reactions · 1 pathways
Cofactors used
What it does, reaction by reaction
1 reactions
Bile Acid Synthesis Lipid Metabolism · ER + mitochondrion + peroxisome
step 2
Irreversible/directional
7-alpha-hydroxycholesterol -> cholic acid or chenodeoxycholic acid
Converts 7-Alpha-hydroxycholesterol into Cholic acid or chenodeoxycholic acid
› Notes
CYP8B1 activity determines the ratio of cholic to chenodeoxycholic acid (the primary bile acids).
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
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