What it does, reaction by reaction
Heme Biosynthesis (Porphyrin Pathway) Amino Acid & Nitrogen Metabolism · Mitochondrion + cytosol
Coproporphyrinogen III + O₂ → protoporphyrinogen IX + 2 CO₂
Converts Coproporphyrinogen III O2 into Protoporphyrinogen IX CO2
› Notes
Mitochondrial intermembrane-space-facing coproporphyrinogen oxidase (CPOX) oxidatively decarboxylates two propionate side chains to vinyl groups. Molecular oxygen is required, and the product re-enters the mitochondrial compartment for final steps.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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