EC 1.1.1.102 KDSR 1 reactions
Enzymes & cofactors
Search by name, gene symbol, EC number or the disorder it causes. Open any enzyme to see every reaction it catalyses, what accelerates it and what inhibits it.
EC 1.13.11.27 HPD 1 reactions
EC 1.13.11.34 ALOX5 1 reactions
Zileuton target; leads to leukotrienes
EC 1.1.1.44 PGD 1 reactions
EC 3.1.1.31 PGLS 1 reactions
ABCA1 1 reactions
EC 2.3.1.26 SOAT1 / SOAT2 1 reactions
EC 6.4.1.2 ACACA 1 reactions
Biotin-dependent; inhibited by AMPK; ACC inhibitors studied in NASH/obesity
EC 3.1.4.12 SMPD1 1 reactions
Niemann-Pick disease types A and B
EC 4.2.1.3 ACO2 1 reactions
EC 1.3.8.- ACADM/ACADVL 1 reactions
MCAD deficiency: hypoketotic hypoglycaemia, dicarboxylic aciduria, SIDS-like presentation
EC 1.3.8.- ACADM/ACADVL 1 reactions
MCAD deficiency: hypoketotic hypoglycaemia, dicarboxylic aciduria, SIDS-like presentation
EC 6.2.1.3 ACSL1-6 1 reactions
SLC25A4 / SLC25A3 1 reactions
EC 2.4.2.7 APRT 1 reactions
EC 3.5.4.4 ADA 1 reactions
ADA deficiency: severe combined immunodeficiency (dATP accumulation inhibits RNR)
EC 2.7.1.20 ADK 1 reactions
EC 6.3.4.4 ADSS2 1 reactions
EC 3.1.1.3 PNPLA2 1 reactions
First and rate-limiting step of adipocyte lipolysis
EC 4.1.1.21 PAICS 1 reactions