unreviewed
4-Hydroxyphenylpyruvate dioxygenase
1 reactions · 1 pathways
Cofactors used
What it does, reaction by reaction
1 reactions
Amino Acid Catabolism Overview (glucogenic vs. ketogenic amino acids; brief overview of branched-chain amino acid catabolism and phenylalanine/tyrosine catabolism as representative examples) Amino Acid & Nitrogen Metabolism · Cytosol + mitochondrion
step 11
Irreversible
4-Hydroxyphenylpyruvate + O₂ → homogentisate + CO₂
Converts 4-Hydroxyphenylpyruvate O2 into Homogentisate CO2
› Notes
4-Hydroxyphenylpyruvate dioxygenase catalyzes oxidative decarboxylation and rearrangement using Fe²⁺. This is an essentially irreversible oxidative step.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
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