Enzymes & cofactors

Search by name, gene symbol, EC number or the disorder it causes. Open any enzyme to see every reaction it catalyses, what accelerates it and what inhibits it.

Enzymes Cofactor terms Vitamins & minerals

Cofactor / coenzyme

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Tyrosine aminotransferase (TAT)

1 reactions

Tyrosine hydroxylase (TH) RL

EC 1.14.16.2 TH 1 reactions

Rate-limiting for catecholamines; BH4-dependent

UDP-galactose 4-epimerase (GALE)

1 reactions

UDP-glucose dehydrogenase (UGDH) RL

EC 1.1.1.22 UGDH 1 reactions

Supplies UDP-glucuronate for conjugation and GAG synthesis

UDP-glucuronosyltransferase (UGT)

EC 2.4.1.17 UGT 1 reactions

Principal phase II route; UGT1A1 clears bilirubin and irinotecan metabolite SN-38

UMP/CMP kinase

1 reactions

Uridine phosphorylase

EC 2.4.2.3 UPP1 1 reactions

Uroporphyrinogen III synthase (UROS)

EC 4.2.1.75 UROS 1 reactions

Vitamin D 25-hydroxylase (CYP2R1/CYP27A1)

EC 1.14.14.24 CYP2R1 / CYP27A1 1 reactions

Vitamin K epoxide reductase (VKORC1) RL

EC 1.17.4.4 VKORC1 1 reactions

Warfarin target; VKORC1 genotype drives dose variability

VKORC1 / NQO1 quinone reductase

1 reactions

ACC2 (muscle-associated isoform)

0 reactions

ALAS1 (hepatic)

0 reactions

ALAS2 (erythroid)

0 reactions

ALT (GPT)

0 reactions

APRT

0 reactions

AST (GOT)

0 reactions

ATGL

0 reactions

BCAT

0 reactions

BCKDH complex

0 reactions