unreviewed
Vitamin D 25-hydroxylase (CYP2R1/CYP27A1)
1 reactions · 1 pathways
Cofactors used
What it does, reaction by reaction
1 reactions
Vitamin D Activation Cofactor & Vitamin Metabolism · Skin, liver ER, renal proximal tubule mitochondria
step 2
Irreversible/directional
Cholecalciferol -> 25-hydroxycholecalciferol (calcidiol)
Converts Cholecalciferol (vitamin D3) into 25-Hydroxycholecalciferol
› Notes
Hepatic and essentially unregulated, so serum 25-OH-D is the storage form and the assay used to assess vitamin D status.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
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