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MS
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BCKDH complex

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Amino Acid Catabolism Overview (glucogenic vs. ketogenic amino acids; brief overview of branched-chain amino acid catabolism and phenylalanine/tyrosine catabolism as representative examples)

Accelerated by

Dephosphorylation by BCKDH phosphatase; elevated branched-chain keto acids

Inhibited by

Phosphorylation by BCKDH kinase; product/high-energy signals

Hormonal control

Insulin promotes BCAA uptake and protein synthesis; fasting, exercise, and cortisol favor BCAA oxidation indirectly

Recent literature

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