unreviewed

ALAS1 (hepatic)

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

Regulation is pathway-specific, so each context is listed separately

1 entries

Accelerated by

Heme depletion; increased apo-cytochrome P450 demand; some drugs/xenobiotics

Inhibited by

Heme/hemin feedback; high carbohydrate/glucose suppresses induction

Hormonal control

Fasting and glucagon favor expression; carbohydrate/insulin suppresses ALAS1 induction; CYP-inducing drugs increase demand indirectly

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