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MS
unreviewed

VKORC1 / NQO1 quinone reductase

1 reactions · 1 pathways

Cofactors used

What it does, reaction by reaction

1 reactions

Vitamin K Cycle Cofactor & Vitamin Metabolism · ER membrane

step 3 Irreversible/directional

Vitamin K quinone + NAD(P)H -> vitamin K hydroquinone

Converts Vitamin K quinone NAD(P)H into Vitamin K hydroquinone

Notes

The NQO1-dependent bypass explains why high-dose vitamin K can overcome warfarin.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

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