Enzymes & cofactors
Search by name, gene symbol, EC number or the disorder it causes. Open any enzyme to see every reaction it catalyses, what accelerates it and what inhibits it.
MCAD deficiency: hypoketotic hypoglycaemia, dicarboxylic aciduria, SIDS-like presentation
MCAD deficiency: hypoketotic hypoglycaemia, dicarboxylic aciduria, SIDS-like presentation
Requires the same five cofactors as PDC; thiamine-sensitive
MAOI + tyramine: hypertensive crisis
SDH mutations: paraganglioma, phaeochromocytoma, GIST; inhibited by malonate
FAD/riboflavin-dependent; links GSH recycling to the pentose phosphate pathway
MTHFR variants: hyperhomocysteinaemia
MAOI + tyramine: hypertensive crisis
NO -> cGMP; nitrate and PDE5-inhibitor axis
SDH mutations: paraganglioma, phaeochromocytoma, GIST; inhibited by malonate
Showing all 16 enzymes.