unreviewed
Monoamine oxidase (MAO-A/MAO-B)
1 reactions · 1 pathways
Cofactors used
Clinical / pharmacological. MAOI + tyramine: hypertensive crisis
What it does, reaction by reaction
1 reactions
Phase I - Functionalization Xenobiotic & Drug Metabolism · Smooth ER (microsomes), mitochondria
step 3
Irreversible/directional
Amine + O2 + H2O -> aldehyde + NH3 + H2O2
Converts Amine O2 H2O into NH3 H2O2
› Notes
Outer mitochondrial membrane; MAO inhibition plus dietary tyramine causes hypertensive crisis.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
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