CoA-SH

• consumed Dihydrolipoyl transacetylase (E2) Pyruvate Oxidation / Link Reaction (Pyruv… ST-0013

  Acetyl-lipoamide + CoA-SH → acetyl-CoA + dihydrolipoamide

• consumed Long-chain acyl-CoA synthetase (ACSL/thiokinase) Beta-Oxidation of Fatty Acids ST-0073

  Fatty acid + CoA-SH + ATP → fatty acyl-CoA + AMP + PPi

• consumed Carnitine palmitoyltransferase II (CPT-2) Beta-Oxidation of Fatty Acids ST-0076

  Acylcarnitine + CoA-SH → fatty acyl-CoA + carnitine

• consumed beta-Ketothiolase (acyl-CoA acetyltransferase) Beta-Oxidation of Fatty Acids ST-0080

  3-Ketoacyl-CoA + CoA-SH → acetyl-CoA + fatty acyl-CoA shortened by two carbons

• consumed ATP-citrate lyase (ACLY) Fatty Acid Synthesis (De Novo Lipogenesis) ST-0061

  Citrate (cytosol) + ATP + CoA-SH → acetyl-CoA + oxaloacetate + ADP + Pi

• consumed Long-chain acyl-CoA synthetase (ACSL) Fatty Acid Synthesis (De Novo Lipogenesis) ST-0072

  Palmitate + CoA + ATP → palmitoyl-CoA + AMP + PPi

• consumed Mitochondrial thiolase (acetyl-CoA acetyltransferase, T2/ACAT1) Ketolysis (Ketone Body Utilization) ST-0089

  Acetoacetyl-CoA + CoA-SH → 2 acetyl-CoA

• consumed Acyl-CoA synthetases Triacylglycerol Synthesis and Lipolysis ST-0105

  Fatty acid + CoA-SH + ATP → fatty acyl-CoA + AMP + PPi

• consumed Branched-chain alpha-ketoacid dehydrogenase complex (BCKDH) Amino Acid Catabolism Overview (glucogeni… ST-0150 rate-limiting

  Branched-chain α-keto acid + CoA + NAD⁺ → branched-chain acyl-CoA + CO₂ + NADH

• consumed Alpha-ketoglutarate dehydrogenase complex Citric Acid Cycle (TCA / Krebs Cycle) ST-0272

  Alpha-ketoglutarate + CoA-SH + NAD+ → succinyl-CoA + CO2 + NADH + H+

• consumed Dihydrolipoyl transacetylase (E2) Pyruvate Dehydrogenase Complex (Link Reac… ST-0266

  Acetyl-dihydrolipoamide-E2 + CoA-SH → acetyl-CoA + dihydrolipoamide-E2

Showing all 11 reactions.