Glutamate
Reactions involving Glutamate
Every recorded step where this molecule takes part
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Pyruvate + glutamate -> alanine + alpha-ketoglutarate (muscle)
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consumed gamma-Glutamylcysteine synthetase (GCL) Glutathione Metabolism (gamma-Glutamyl Cy… ST-0336 rate-limiting
L-Glutamate + L-cysteine + ATP -> gamma-glutamylcysteine + ADP + Pi
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L-Glutamate -> GABA + CO2
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L-glutamate + NAD⁺ (or NADP⁺) + H₂O ⇌ α-ketoglutarate + NH₄⁺ + NADH (or NADPH) + H⁺
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consumed Glutamate-aspartate antiporter (citrin/aralar, SLC25A13/12) Malate-Aspartate Shuttle ST-0357
Aspartate(matrix) + glutamate(cytosol) -> aspartate(cytosol) + glutamate(matrix)
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Alanine + alpha-ketoglutarate -> pyruvate + glutamate (liver)
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produced Aminotransferases + glutamate dehydrogenase (PLP-dependent nitrogen removal) Amino Acid Catabolism Overview (glucogeni… ST-0146
Amino acid + α-ketoglutarate ⇌ corresponding α-keto acid + glutamate
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Leucine/isoleucine/valine + α-ketoglutarate ⇌ their respective branched-chain α-keto acids + glutamate
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L-tyrosine + α-ketoglutarate ⇌ 4-hydroxyphenylpyruvate + glutamate
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L-glutamine + H₂O → L-glutamate + NH₄⁺
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E-PMP + α-ketoglutarate → E-PLP + L-glutamate
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L-alanine + α-ketoglutarate ⇌ pyruvate + L-glutamate
Pathway junctions through this molecule
Produced in one pathway, consumed in another
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Advances and perspectives in genetically encoded biosensors for biomarker detection and theranostic circuits.
Xu J, Qi Q, Wang Q. · 2026-09-23
open access unreviewed -
2
Systems-level analysis of 1,6-hexanediol stress response and tolerance engineering in <i>Escherichia coli</i>.
Zhang X, Qin L, Li H, Wang X, Chen K. · 2026-08-15
open access unreviewed -
3
Metabolic engineering of <i>Escherichia coli</i> for efficient production of d-phenylglycine.
Xiong Y, Shang Z, Lu L, Wang T, Cai G, Shen X, Sun X, Wang J, Yuan Q. · 2026-08-07
open access unreviewed -
4
System reconstruction of <i>Bacillus licheniformis</i> for efficient expression of alkaline protease.
Zhang Q, Zhang M, Zhu Z, Ma H, Mo F, Lei J, He S, Liao Y, Yan S, Cai D, Chen S. · 2026-08-01
open access unreviewed -
5
A multifunctional MOF-mineralized conductive hydrogel coating on zinc implants orchestrates neuro-osteogenic coupling for enhanced bone defect repair.
Wei Y, Mo D, Pan M, Yang T, Li X, Ye L, Li J, Yuan L, Bei Z, Qian Z. · 2026-09-03
open access unreviewed -
6
Going high-throughput: Dynamic conformations and interactions <i>in vivo</i>.
Gong Z, Zhao Q, Sun M, Zhang B, Zhang X, Zhang L, Zhang Y, Liu M. · 2026-08-04
open access unreviewed -
7
N-terminal fusion length: The key to reliable and context-preserving regulatory sequence characterization.
Yang S, Liu Y, Li A, Wang S, Cui J, Liu H, Wang M, Mao Y. · 2026-07-22
open access unreviewed -
8
Predictions and cross-center validation of IDH status and 1p/19q status in adult diffuse glioma with non-invasive magnetic resonance spectroscopy.
Tu Z, Hu W, Zhang J, Xing Z, Li J, Xu J, Lin M, Jiang X, Cao D, Zhang J, Guo D, Qu X. · 2026-06-01
open access unreviewed -
9
Real-time NMR analysis of glutamine metabolism for screening anti-cancer agents in living cells.
Lei Y, Huang T, Chai X, Fan X, He S, Liu C, Liu M, Zhang X. · 2026-06-12
open access unreviewed -
10
Engineering short-sequence elements for condensate-like assemblies by de novo design.
Zhang D, Zhang B, Zheng C, Sun W, Niu H, Zhu C, Chen Y, Liu D, Ying H. · 2026-07-18
cited 1× open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.