unreviewed
Glutamate-aspartate antiporter (citrin/aralar, SLC25A13/12)
1 reactions · 1 pathways
What it does, reaction by reaction
1 reactions
Malate-Aspartate Shuttle Energy Metabolism & Cellular Respiration · Cytosol + inner mitochondrial membrane
step 5
Irreversible/directional
Aspartate(matrix) + glutamate(cytosol) -> aspartate(cytosol) + glutamate(matrix)
Converts Aspartate(matrix) Glutamate into Aspartate(cytosol) Glutamate
› Notes
Completes the cycle; cytosolic AST (GOT1) then reforms oxaloacetate. Dominant shuttle in liver, kidney and heart.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
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