Pyruvate
Reactions involving Pyruvate
Every recorded step where this molecule takes part
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Pyruvate + HCO3− + ATP → oxaloacetate + ADP + Pi
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Pyruvate + glutamate -> alanine + alpha-ketoglutarate (muscle)
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Pyruvate + thiamine pyrophosphate (TPP) → hydroxyethyl-TPP + CO2
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Pyruvate + NADH + H+ ⇌ lactate + NAD+
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Pyruvate + TPP → hydroxyethyl-TPP + CO2
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Lactate -> pyruvate -> glucose (liver, 6 ATP equivalents)
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Alanine + alpha-ketoglutarate -> pyruvate + glutamate (liver)
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Phosphoenolpyruvate + ADP → pyruvate + ATP
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Malate + NADP+ → pyruvate + CO2 + NADPH + H+
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produced Multiple pathway-specific catabolic enzymes Amino Acid Catabolism Overview (glucogeni… ST-0147
Glucogenic carbon skeleton → pyruvate or a gluconeogenic TCA-cycle intermediate
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L-alanine + α-ketoglutarate ⇌ pyruvate + L-glutamate
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Phosphoenolpyruvate + ADP → pyruvate + ATP
Showing all 12 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Kunkui Baoshen Granule attenuates diabetic kidney disease via the SIRT3/FOXO3a signaling pathway: An integrated multi-omics analysis.
Wei Y, Zhang S, Yu X, Tan Y, Zha M, Yu J. · 2026-07-15
unreviewed -
2
Metabolic engineering of <i>Escherichia coli</i> based on adaptive evolution and omics technology for highly efficient l-valine production under oxygen-limited conditions.
Zhang H, Ha Z, Wei A, Zhao C, Meng G, Li X, Wu F, Liu J, Wu H, Ma Q, Xie X. · 2026-06-18
unreviewed -
3
Metabolomics-driven insights into the multi-target antibacterial mechanisms of 2-methoxycinnamaldehyde against Bacillus cereus and its application in pork preservation.
Li X, Xiang R, Tan Y, He F, Huang T, Wang J, Yin K, Shi X, Wang Y, Tu J, Xia X, Li J. · 2026-06-10
unreviewed -
4
mTORC2-Na<sub>v</sub>1.2 signaling drives early hyperexcitability in Alzheimer's disease mouse model.
Dvorak NM, Noebels JL. · 2026-06-22
open access unreviewed -
5
Metabolic profile association with white matter hyperintensity in patients with mild cognitive impairment.
Ariaei A, Zamiri R, Ghasemi A, Rezayani B, Rezayani S, Ezatpour A, Farshidi N, Sheikhi EA, Roghanian A, Alzhe… · 2026-06-09
open access unreviewed -
6
Long-term expandable auricular chondrocytes reveal a conserved nine-gene decline module underlying senescence-independent dedifferentiation.
Alemujiang D, Tsuji N, Sakamoto T, Chu YY, Hoshi K, Hikita A. · 2026-06-13
open access unreviewed -
7
Metabolic engineering of <i>Vibrio natriegens</i> for the efficient biosynthesis of ergothioneine from sucrose using non-sterile fed-batch fermentation.
Liang X, Wang Y, Lv Y, Huang C, Huang Z, Wei J, Jiang S, Dong Z, Zhou Z, Lin M. · 2026-06-12
open access unreviewed -
8
Thermodynamic metabolic modeling of growth and bioproduction potential of the acetogen <i>Acetobacterium woodii</i> with and without redox cofactor swaps.
Bauer J, von Kamp A, Pflügl S, Klamt S. · 2026-06-13
open access unreviewed -
9
Indole-3-acetic acid production is rare among gut bacteria and reflects OFOR-driven amino acid oxidation in acetogens.
DeFeo ME, Liu Y, Zhou Z, Higginbottom SK, Dodd D. · 2026-06-21
open access unreviewed -
10
Mapping the metagenomic landscape: combined shotgun sequencing and quantitative PCR to profile gut metagenome-assembled genomes in marmosets following treatment with a broad-spectrum antibiotic cocktail.
Hernandez JB, Abiodun M, Hayer SS, Dickson T, Ayayee P, Clayton JB. · 2026-06-21
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.