Pyruvate

• consumed Mitochondrial pyruvate carboxylase Gluconeogenesis ST-0016

  Pyruvate + HCO3− + ATP → oxaloacetate + ADP + Pi

• consumed Alanine aminotransferase (ALT/GPT) Glucose-Alanine Cycle ST-0381

  Pyruvate + glutamate -> alanine + alpha-ketoglutarate (muscle)

• consumed Pyruvate dehydrogenase E1 Pyruvate Oxidation / Link Reaction (Pyruv… ST-0011

  Pyruvate + thiamine pyrophosphate (TPP) → hydroxyethyl-TPP + CO2

• consumed Lactate dehydrogenase (LDH) Anaerobic Glycolysis / Lactic Acid Fermen… ST-0298

  Pyruvate + NADH + H+ ⇌ lactate + NAD+

• consumed Pyruvate dehydrogenase E1 Pyruvate Dehydrogenase Complex (Link Reac… ST-0264

  Pyruvate + TPP → hydroxyethyl-TPP + CO2

• produced Lactate dehydrogenase (LDHB) + gluconeogenic enzymes Cori Cycle (lactate shuttle) ST-0380

  Lactate -> pyruvate -> glucose (liver, 6 ATP equivalents)

• produced Alanine aminotransferase (ALT/GPT) Glucose-Alanine Cycle ST-0382

  Alanine + alpha-ketoglutarate -> pyruvate + glutamate (liver)

• produced Pyruvate kinase Glycolysis ST-0010

  Phosphoenolpyruvate + ADP → pyruvate + ATP

• produced Cytosolic, NADP+-dependent malic enzyme Fatty Acid Synthesis (De Novo Lipogenesis) ST-0063

  Malate + NADP+ → pyruvate + CO2 + NADPH + H+

• produced Multiple pathway-specific catabolic enzymes Amino Acid Catabolism Overview (glucogeni… ST-0147

  Glucogenic carbon skeleton → pyruvate or a gluconeogenic TCA-cycle intermediate

• produced Alanine aminotransferase (ALT / GPT) Transamination ST-0135

  L-alanine + α-ketoglutarate ⇌ pyruvate + L-glutamate

• produced Pyruvate kinase Anaerobic Glycolysis / Lactic Acid Fermen… ST-0297

  Phosphoenolpyruvate + ADP → pyruvate + ATP

Showing all 12 reactions.