UDP

• consumed Ribonucleotide reductase (RNR, class Ia) Deoxyribonucleotide Formation (Ribonucleo… ST-0252 rate-limiting

  Nucleoside diphosphates → deoxyribonucleoside diphosphates

• consumed Nucleoside diphosphate kinase (NDPK/NME) Pyrimidine De Novo Synthesis (through to … ST-0231

  UDP → UTP

• consumed Ribonucleotide reductase (RNR) Pyrimidine De Novo Synthesis (through to … ST-0233

  UDP → dUDP (route to dUMP)

• produced Glycogenin (autoglucosylation) Glycogenesis (Glycogen Synthesis) ST-0032

  UDP-glucose + glycogenin–Tyr-OH → glycogenin–Tyr-O-glucose + UDP; repeated additions form a short alpha(1→4)-glucosyl primer

• produced Glycogen synthase Glycogenesis (Glycogen Synthesis) ST-0033 rate-limiting

  UDP-glucose + glycogen(n) → glycogen(n+1) + UDP

• produced Glucosylceramide synthase (UGCG) Sphingolipid Synthesis ST-0329

  Ceramide + UDP-glucose -> glucosylceramide + UDP

• produced Bilirubin UDP-glucuronosyltransferase (UGT1A1) Heme Degradation (Bilirubin Pathway) ST-0188 rate-limiting

  Bilirubin + 2 UDP-glucuronic acid → bilirubin mono- and predominantly diglucuronide + 2 UDP

• produced Nucleoside diphosphate kinases/phosphatases (NTP<->NDP pool) Deoxyribonucleotide Formation (Ribonucleo… ST-0262

  Ribonucleoside triphosphates → dNDP precursor pool

• produced UMP/CMP kinase Pyrimidine De Novo Synthesis (through to … ST-0230

  UMP → UDP

• produced UDP-glucuronosyltransferase (UGT) Phase II - Conjugation ST-0370

  Substrate + UDP-glucuronate -> glucuronide + UDP

Showing all 10 reactions.