What it does, reaction by reaction
Glycogenesis (Glycogen Synthesis) Carbohydrate Metabolism · Cytosol (glycogen particle)
UDP-glucose + glycogenin–Tyr-OH → glycogenin–Tyr-O-glucose + UDP; repeated additions form a short alpha(1→4)-glucosyl primer
Converts UDP-glucose Glycogenin-Tyr-OH into Glycogenin-Tyr-O-glucose UDP Repeated additions form a short alpha(1→4)-glucosyl primer
› Notes
Glycogenin is an autoglycosylating protein that uses UDP-glucose and divalent cation (typically Mg2+). It creates the required primer, usually about 8 residues long, because glycogen synthase cannot initiate a new chain de novo.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
Glycogenesis (Glycogen Synthesis)
Listed there as: Glycogenin
Availability of UDP-glucose
Lack of primer function
No major acute independent hormonal regulation
Recent literature
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