Nucleoside diphosphate kinases/phosphatases (NTP<->NDP pool)
What it does, reaction by reaction
Deoxyribonucleotide Formation (Ribonucleotide Reductase pathway and thymidylate synthesis) Nucleotide Metabolism · Cytosol
Ribonucleoside triphosphates → dNDP precursor pool
Converts ATP GTP CTP UTP into ADP GDP CDP UDP
› Notes
Nucleoside diphosphate phosphatases/kinases maintain interconversion between NTP and NDP pools so that ADP, GDP, CDP, and UDP are available to RNR. RNR acts on diphosphates, not directly on NTPs, a feature central to its allosteric substrate-specificity system.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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