EC 1.5.1.3 DHFR 3 reactions
Target of methotrexate, trimethoprim, pyrimethamine
Enzymes & cofactors
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Showing enzymes whose reactions use THF (folate).
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EC 2.1.1.45 TYMS 3 reactions
Target of 5-fluorouracil (via FdUMP)
EC 2.1.2.3 ATIC 2 reactions
EC 2.1.2.2 GART 2 reactions
EC 2.1.1.13 MTR 2 reactions
B12-dependent; deficiency causes megaloblastic anaemia and the methyl-folate trap
EC 2.1.2.1 SHMT1 / SHMT2 2 reactions
EC 6.3.4.3 MTHFD1 1 reactions
1 reactions
EC 1.5.1.5 MTHFD1 1 reactions
EC 1.5.1.20 MTHFR 1 reactions
MTHFR variants: hyperhomocysteinaemia
Showing all 10 enzymes.