Malate
Reactions involving Malate
Every recorded step where this molecule takes part
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Malate + NAD+ ↔ oxaloacetate + NADH + H+
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Malate + NADP+ → pyruvate + CO2 + NADPH + H+
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L-Malate + NAD+ ⇌ oxaloacetate + NADH + H+
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Malate + NAD+ -> oxaloacetate + NADH + H+ (matrix)
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Oxaloacetate + NADH + H+ ↔ malate + NAD+
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Oxaloacetate + NADH + H+ → malate + NAD+
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Fumarate + H2O ⇌ L-malate
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Cytosolic oxaloacetate + NADH + H+ -> malate + NAD+
Showing all 8 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Citric Acid Cycle (TCA / Krebs Cycle) | → | Fatty Acid Synthesis (De Novo Lipogenesis) | cross-category |
| Citric Acid Cycle (TCA / Krebs Cycle) | → | Gluconeogenesis | cross-category |
| Citric Acid Cycle (TCA / Krebs Cycle) | → | Malate-Aspartate Shuttle | within category |
| Fatty Acid Synthesis (De Novo Lipogenesis) | → | Citric Acid Cycle (TCA / Krebs Cycle) | cross-category |
| Fatty Acid Synthesis (De Novo Lipogenesis) | → | Gluconeogenesis | cross-category |
| Fatty Acid Synthesis (De Novo Lipogenesis) | → | Malate-Aspartate Shuttle | cross-category |
| Gluconeogenesis | → | Citric Acid Cycle (TCA / Krebs Cycle) | cross-category |
| Gluconeogenesis | → | Fatty Acid Synthesis (De Novo Lipogenesis) | cross-category |
| Gluconeogenesis | → | Malate-Aspartate Shuttle | cross-category |
| Malate-Aspartate Shuttle | → | Citric Acid Cycle (TCA / Krebs Cycle) | within category |
| Malate-Aspartate Shuttle | → | Fatty Acid Synthesis (De Novo Lipogenesis) | cross-category |
| Malate-Aspartate Shuttle | → | Gluconeogenesis | cross-category |
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Unlocking raw-corncob consolidated bioprocessing for malic acid production by DyP-enabled lignin deconstruction in <i>Myceliophthora thermophila</i>.
Zhang Y, Zhang Y, Han L, Liu J, Liu D, Sun T, Wang D, Li M, Li J, Tian C. · 2026-08-08
open access unreviewed -
2
Metabolic engineering of <i>Escherichia coli</i> for efficient production of d-phenylglycine.
Xiong Y, Shang Z, Lu L, Wang T, Cai G, Shen X, Sun X, Wang J, Yuan Q. · 2026-08-07
open access unreviewed -
3
Dismantling the eDNA-mediated H<sub>2</sub>S barrier with biohybrids against refractory biofilm infections.
Yin M, Su M, Yi J, Ren Y, Zhang Y, Wu Q, Yang C, Xiao S, Gao C, Tang R, Cheng B, Xia J. · 2026-09-15
open access unreviewed -
4
Engineering nonconventional yeasts to produce carboxylic acids: Advances and Prospects.
Zhang L, Fan Y, Shi W, Zhou X. · 2026-07-16
open access unreviewed -
5
Mitochondria-derived peptide hydrogel augments mitochondrial transplantation for promoting cardiac repair via macrophage metabolic reprogramming.
Li H, Zhang Y, Jian Y, Fang F, Ouyang W, Zhuang D, Ju W, Gao R, Gao Y, Kang S, Kong P, Li Y, Pan X, Wang W, F… · 2026-08-14
open access unreviewed -
6
Advancing our understanding of photosynthesis: discoveries and insights from aquatic plants.
Kazmi A, Li G, Yang J, Zhao X, Islam MF, Li X, Kimura S, Hou H. · 2026-06-29
open access unreviewed -
7
Data-driven optimization of salt shock for high-efficiency ectoine production in <i>Halomonas elongata</i>.
Yu J, Gu Q, Ji S, Liu H, Zhang Y, Li C, Zhuang Y, Wang Z. · 2026-06-18
open access unreviewed -
8
Creatine supplementation in soccer players: a systematic review.
Ashtary-Larky D, Candow DG, Antonio J, Quiceno C, Angelini F, Forbes SC, Moradi S, Kazeminasab F, Bagheri R. · 2026-10-02
open access unreviewed -
9
An integrated analytical method for the separation, identification and quantification of carotenoids in Rhodobacter capsulatus.
Llama J, Jerez S, Ventura M, Prado A, Puyol D, Melero JA. · 2026-09-11
open access unreviewed -
10
Responses of arbuscular mycorrhizal wheat to salinity: from symbiotic signaling to stress adaptation.
Zamir H, Rauf F, Jamali ZH, Khan S, Zulfiqar U, Alotaibi MS, Muminov M, Abdusamatov S, Gururani MA, Korai SK. · 2026-09-23
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.