unreviewed
Fumarase (fumarate hydratase)
1 reactions · 1 pathways
Cofactors used
Clinical / pharmacological. FH mutations: hereditary leiomyomatosis and renal cell carcinoma
What it does, reaction by reaction
1 reactions
Citric Acid Cycle (TCA / Krebs Cycle) Energy Metabolism & Cellular Respiration · Mitochondrial matrix
step 7
Reversible
Fumarate + H2O ⇌ L-malate
Converts Fumarate H2O into Malate
› Notes
Required cofactor: none beyond water. The reaction is reversible and forms only L-malate.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
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