unreviewed
Mitochondrial malate dehydrogenase (MDH2)
1 reactions · 1 pathways
Cofactors used
What it does, reaction by reaction
1 reactions
Malate-Aspartate Shuttle Energy Metabolism & Cellular Respiration · Cytosol + inner mitochondrial membrane
step 3
Reversible
Malate + NAD+ -> oxaloacetate + NADH + H+ (matrix)
Converts Malate NAD+ into Oxaloacetate NADH H+
› Notes
Regenerates matrix NADH, which enters at Complex I - hence ~2.5 ATP per cytosolic NADH.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
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