Malate
Reactions involving Malate
Every recorded step where this molecule takes part
-
Malate + NAD+ ↔ oxaloacetate + NADH + H+
-
Malate + NADP+ → pyruvate + CO2 + NADPH + H+
-
L-Malate + NAD+ ⇌ oxaloacetate + NADH + H+
-
Malate + NAD+ -> oxaloacetate + NADH + H+ (matrix)
-
Oxaloacetate + NADH + H+ ↔ malate + NAD+
-
Oxaloacetate + NADH + H+ → malate + NAD+
-
Fumarate + H2O ⇌ L-malate
-
Cytosolic oxaloacetate + NADH + H+ -> malate + NAD+
Showing all 8 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Citric Acid Cycle (TCA / Krebs Cycle) | → | Fatty Acid Synthesis (De Novo Lipogenesis) | cross-category |
| Citric Acid Cycle (TCA / Krebs Cycle) | → | Gluconeogenesis | cross-category |
| Citric Acid Cycle (TCA / Krebs Cycle) | → | Malate-Aspartate Shuttle | within category |
| Fatty Acid Synthesis (De Novo Lipogenesis) | → | Citric Acid Cycle (TCA / Krebs Cycle) | cross-category |
| Fatty Acid Synthesis (De Novo Lipogenesis) | → | Gluconeogenesis | cross-category |
| Fatty Acid Synthesis (De Novo Lipogenesis) | → | Malate-Aspartate Shuttle | cross-category |
| Gluconeogenesis | → | Citric Acid Cycle (TCA / Krebs Cycle) | cross-category |
| Gluconeogenesis | → | Fatty Acid Synthesis (De Novo Lipogenesis) | cross-category |
| Gluconeogenesis | → | Malate-Aspartate Shuttle | cross-category |
| Malate-Aspartate Shuttle | → | Citric Acid Cycle (TCA / Krebs Cycle) | within category |
| Malate-Aspartate Shuttle | → | Fatty Acid Synthesis (De Novo Lipogenesis) | cross-category |
| Malate-Aspartate Shuttle | → | Gluconeogenesis | cross-category |
Recent literature
Europe PMC · from cache · sorted by publication date
-
1
Hormone-metabolism crosstalk in plants: an integrated signaling network coordinating growth and stress adaptation.
Murtaza G, Ahmed Z, Ullah S, Alotaibi MS, Ali S, Iqbal R. · 2026-07-30
unreviewed -
2
Role of primary protectors of plant cells in salinity tolerance: molecular mechanisms and adaptive strategies.
Das S, Janeeshma E, Mousavi H, Aronsson H, Sarraf M. · 2026-06-12
open access unreviewed -
3
The acetylation mechanism and engineering strategy of isocitrate lyase for optimizing biosynthesis in <i>Escherichia coli</i>.
Jia R, Wang J, Zhang Y, Xian M, Qi Q, Liu M, Zhao G. · 2026-05-23
open access unreviewed -
4
A commensal protozoan exacerbates acetaminophen-induced liver injury by producing free sphingosine.
Yan X, Shen Y, Sun Q, Zhu X, Chen Q, Liao L, Zhou Y, Cheng W, Shi Z, Liu Z, Wei Y, Liu X, Wang Y, Kou Y. · 2026-06-02
open access unreviewed -
5
The role of protein palmitoylation in disease pathogenesis and therapeutic innovation.
Lin X, Xing J, Jia K, Liu S, Liu Y, Gu Y, Guo K, Yi J. · 2026-05-29
open access unreviewed -
6
The plasma metabolome and clinical features of patients with coeliac disease in Northwest China.
Zhang W, Wu X, Li Y, Huang Z, Hui W, Shi T, Lu W, Bai H, Wu Q, Wang M, Liu K, Xu L, Gao F, Wu J. · 2026-05-16
open access unreviewed -
7
Metabolic reprogramming in plant defense: linking signaling networks to metabolomics-driven insights.
Khan S, Korai Z, Yang L, Korai SK, Li S, Zulfiqar U, Alotaibi MS, Asadullaeva D, Muminov M, Gururani MA, Wang… · 2026-05-13
open access unreviewed -
8
Organic acids counteract the determinate root development induced by phosphate deprivation in <i>Arabidopsis thaliana</i>.
Corona-Sánchez I, López-Bucio J, Villalobos-Escobedo JM, Vázquez-Fuentes S, Campos-García J, Cruz HR, López-B… · 2026-04-23
open access unreviewed -
9
Gut microbiota reshapes host energy metabolism to modulate depressive behaviors.
Lei P, Qi Z, Ma Q, Zhao B, Wen B, Jiang W, Xi W, Liu Y, Xun Y, Zhang S, Wang Y, Guo Y, Wang W, Ma X, Jia M, F… · 2026-04-23
open access unreviewed -
10
Discovery of functional compounds from dimorphic edible <i>Ophiocordyceps sinensis</i> fungus in host haemolymph.
Sun T, Yang Y, Xie J, Rao Z, Han R, Cao L. · 2026-04-17
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.