Common carrier Cofactor / common carrier unreviewed

CO2

Pathways

Reactions involving CO2

Every recorded step where this molecule takes part

All 20 Consumed 1 Produced 19

produced Mitochondrial ALA synthase (ALAS) Heme Biosynthesis (Porphyrin Pathway) ST-0177 rate-limiting

Glycine + succinyl-CoA → δ-aminolevulinate (ALA) + CO₂ + CoA
produced Cytosolic uroporphyrinogen decarboxylase (UROD) Heme Biosynthesis (Porphyrin Pathway) ST-0181

Uroporphyrinogen III → coproporphyrinogen III + 4 CO₂
produced Coproporphyrinogen oxidase (CPOX) Heme Biosynthesis (Porphyrin Pathway) ST-0182

Coproporphyrinogen III + O₂ → protoporphyrinogen IX + 2 CO₂
produced Glutamate decarboxylase (GAD65/GAD67) Other Neurotransmitter Synthesis ST-0349

L-Glutamate -> GABA + CO2
produced Histidine decarboxylase (HDC) Other Neurotransmitter Synthesis ST-0350

L-Histidine -> histamine + CO2
produced Aromatic L-amino acid decarboxylase (DDC) Serotonin & Melatonin Synthesis ST-0347

5-Hydroxytryptophan -> serotonin (5-HT) + CO2
produced Alpha-ketoglutarate dehydrogenase complex Citric Acid Cycle (TCA / Krebs Cycle) ST-0272

Alpha-ketoglutarate + CoA-SH + NAD+ → succinyl-CoA + CO2 + NADH + H+
produced Pyruvate dehydrogenase E1 Pyruvate Dehydrogenase Complex (Link Reac… ST-0264

Pyruvate + TPP → hydroxyethyl-TPP + CO2

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