Fatty acyl-CoA
Reactions involving Fatty acyl-CoA
Every recorded step where this molecule takes part
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consumed Carnitine palmitoyltransferase I (CPT-1) Beta-Oxidation of Fatty Acids ST-0074 rate-limiting
Fatty acyl-CoA + carnitine → acylcarnitine + CoA-SH
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Fatty acyl-CoA + FAD → trans-Δ2-enoyl-CoA + FADH2
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Sphinganine + fatty acyl-CoA -> dihydroceramide + CoA-SH
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consumed Glycerol-3-phosphate acyltransferase (GPAT) Triacylglycerol Synthesis and Lipolysis ST-0108
Glycerol-3-phosphate + fatty acyl-CoA → lysophosphatidic acid (1-acyl-glycerol-3-phosphate) + CoA-SH
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consumed 1-Acylglycerol-3-phosphate acyltransferase (AGPAT) Triacylglycerol Synthesis and Lipolysis ST-0109
Lysophosphatidic acid + fatty acyl-CoA → phosphatidic acid (1,2-diacyl-glycerol-3-phosphate) + CoA-SH
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consumed Diacylglycerol acyltransferase (DGAT1 or DGAT2) Triacylglycerol Synthesis and Lipolysis ST-0111
DAG + fatty acyl-CoA → TAG + CoA-SH
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Fatty acid + CoA-SH + ATP → fatty acyl-CoA + AMP + PPi
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Acylcarnitine + CoA-SH → fatty acyl-CoA + carnitine
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Fatty acid + CoA-SH + ATP → fatty acyl-CoA + AMP + PPi
Showing all 9 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Beta-Oxidation of Fatty Acids | → | Sphingolipid Synthesis | within category |
| Beta-Oxidation of Fatty Acids | → | Triacylglycerol Synthesis and Lipolysis | within category |
| Triacylglycerol Synthesis and Lipolysis | → | Beta-Oxidation of Fatty Acids | within category |
| Triacylglycerol Synthesis and Lipolysis | → | Sphingolipid Synthesis | within category |
Recent literature
Europe PMC · from cache · sorted by publication date
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1
<i>Streptomyces</i>: boost chassis strains for production of invaluable natural products.
Chen S, Ling S, Li J, Liu Z, Zhang L, Zhang J. · 2026-06-12
open access unreviewed -
2
Mitochondrial dysfunction-ferroptosis crosstalk drives renal fibrosis in chronic kidney disease.
Zeng L, Zhu L, Xu H, Li Y, Hu K. · 2026-05-06
open access unreviewed -
3
A comprehensive review of the physiology and evidence base to guide the use of ergogenic and medical supplements for enhanced cycling performance.
Rowland A, Edwards S, Prieto-Bellver G, Menz B, Rowland A, Cornelisse E, Karapetis CS, Wallen MP, Hopkins AM. · 2026-02-13
open access unreviewed -
4
cAMP-PKA/EPAC signaling pathways: crucial regulators of lipid homeostasis.
Chen C, Gao H, Tian Q, Cao J. · 2026-01-07
open access unreviewed -
5
<i>Lactococcus lactis</i> subsp. Cremoris reprograms systemic metabolism and protects against myocardial injury.
Gacasan CA, Naudin CR, Weinberg J, Askew LC, Barbian ME, Jones DP, Jones RM. · 2026-01-04
cited 1× open access unreviewed -
6
Polystyrene NPs reshape PFOA-driven mitochondrial redox balance, pentose phosphate-nucleotide metabolism, and membrane lipid remodeling in Cipangopaludina cathayensis.
Li H, Wang M, Sun X, Song J. · 2026-07-08
unreviewed -
7
CytoSorb in burn patients with septic shock and acute kidney injury on continuous kidney replacement therapy efficiently reduces the levels of Gram-negative-derived quorum-sensing molecules associated with lactate increases.
Mariano F, Leporati M, Carpenito N, Mella A, Di Vico MC, Skosana P, Pensa A, Depetris N, Risso D, Gambino R, … · 2026-06-05
unreviewed -
8
LINC01186-mediated deubiquitination of ACSL4 reprograms lipid metabolism to increase autophagy-mediated angiogenesis in colorectal cancer.
Li J, Luo Q, Xu C, Ding J, Lu C, Zhan T, Chang L, Wang J, Wang J, Zhu J, Li J, Wang K. · 2026-05-25
unreviewed -
9
Utilization, metabolic regulation and applications of hydrophobic substrates in <i>Yarrowia lipolytica</i>.
Zhu F, Zhang L, Wen J. · 2026-02-18
open access unreviewed -
10
A novel TetR-type repressor directly modulates precursor supply and utilization for erythromycin biosynthesis.
Wu P, Meng Z, Shu Y, Chen K, Xu Z, Huang X, Zhang B, Liu J, Wu H. · 2026-02-03
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.