Diacylglycerol acyltransferase (DGAT1 or DGAT2)
Cofactors used
What it does, reaction by reaction
Triacylglycerol Synthesis and Lipolysis Lipid Metabolism · Cytosol / ER
DAG + fatty acyl-CoA → TAG + CoA-SH
Converts Diacylglycerol Fatty acyl-CoA into Triacylglycerol (TAG) CoA-SH
› Notes
Diacylglycerol acyltransferase (DGAT1 or DGAT2) catalyzes the terminal acylation. This is the final committed step of TAG assembly; TAG is packaged into lipid droplets or, in liver/intestine, into apoB-containing lipoproteins.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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