Glycerol-3-phosphate acyltransferase (GPAT)
Cofactors used
What it does, reaction by reaction
Triacylglycerol Synthesis and Lipolysis Lipid Metabolism · Cytosol / ER
Glycerol-3-phosphate + fatty acyl-CoA → lysophosphatidic acid (1-acyl-glycerol-3-phosphate) + CoA-SH
Converts Glycerol-3-phosphate Fatty acyl-CoA into Lysophosphatidic acid CoA-SH
› Notes
Glycerol-3-phosphate acyltransferase (GPAT) catalyzes the first acylation, usually at sn-1. This is an important regulatory/committing step of the glycerol-3-phosphate pathway.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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