Fumarate
Reactions involving Fumarate
Every recorded step where this molecule takes part
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Fumarate + H2O ⇌ L-malate
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produced Multiple pathway-specific catabolic enzymes Amino Acid Catabolism Overview (glucogeni… ST-0147
Glucogenic carbon skeleton → pyruvate or a gluconeogenic TCA-cycle intermediate
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Fumarylacetoacetate + H₂O → fumarate + acetoacetate
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Argininosuccinate → L-arginine + fumarate
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Succinate + FAD ⇌ fumarate + FADH2 (enzyme-bound); ubiquinone is reduced to ubiquinol in the respiratory chain
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Succinate + Q → fumarate + QH2
Showing all 6 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Amino Acid Catabolism Overview (glucogenic … | → | Citric Acid Cycle (TCA / Krebs Cycle) | cross-category |
| Electron Transport Chain (Complexes I–IV) | → | Citric Acid Cycle (TCA / Krebs Cycle) | within category |
| Urea Cycle | → | Citric Acid Cycle (TCA / Krebs Cycle) | cross-category |
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Unlocking raw-corncob consolidated bioprocessing for malic acid production by DyP-enabled lignin deconstruction in <i>Myceliophthora thermophila</i>.
Zhang Y, Zhang Y, Han L, Liu J, Liu D, Sun T, Wang D, Li M, Li J, Tian C. · 2026-08-08
open access unreviewed -
2
Dismantling the eDNA-mediated H<sub>2</sub>S barrier with biohybrids against refractory biofilm infections.
Yin M, Su M, Yi J, Ren Y, Zhang Y, Wu Q, Yang C, Xiao S, Gao C, Tang R, Cheng B, Xia J. · 2026-09-15
open access unreviewed -
3
Applications and future development of solid-state nuclear magnetic resonance for investigating metal-organic frameworks.
Chen S, Wang ZP, Lucier BEG, Zhang W, Wang W. · 2026-06-18
open access unreviewed -
4
Engineering nonconventional yeasts to produce carboxylic acids: Advances and Prospects.
Zhang L, Fan Y, Shi W, Zhou X. · 2026-07-16
open access unreviewed -
5
Defining biomaterial-driven design principles for bioabsorbable flow diverters: current state and perspectives.
Di Lorenzo A, Mohamed AF, Isella B, Behme D, Loewen A, Vekemans M, Schwab R, Schmitz TC, Jockenhoevel S, Kopp… · 2026-07-31
open access unreviewed -
6
Chemerin - CMKLR1 signaling contributes to immune metabolic dysfunction in salt-sensitive hypertension.
McMillan R, Saleem M, Thorson A, Pierre-Louis O, Desta S, Ertuglu LA, Wanjalla CN, Stolze L, Sheng Q, Mwesigw… · 2026-09-27
unreviewed -
7
Sequential combination of anti-PD-1 antibody and PEG-IFNα in chronic hepatitis B patients: correlates of HBsAg loss with enhanced T-cell responses.
Wang H, Zhang C, Li X, Li Y, Zhang X, Xu R, Wang K, Lv S, Fan X, Wang Q, Liu S, Yang S, Zhang X, Dang S, Wang… · 2026-09-25
open access unreviewed -
8
Ethanol exposure is associated with spatial and taxon-specific gut microbiota remodeling characterized by ecological adaptation rather than broad activation of microbial ethanol metabolism.
Li M, Mao J, Liu S, Yu H, Qin H, Liu X, Tu R, Chen S, Liu Z, Zhang S, Mao J. · 2026-09-25
open access unreviewed -
9
Elevated miR-103b in exosomes derived from brain-metastatic triple-negative breast cancer cells remodels the brain pre-metastatic niche (PMN).
Zhou L, Ke J, Zhang S, Xiao S, Zhang H, Liu S, Liu L, Liu M, Lu Z, Zheng S. · 2026-09-25
open access unreviewed -
10
Acetic acid induces strain-specific metabolic adaptation of <i>Saccharomyces cerevisiae</i> during pH stress.
Azbekyan G, Shirvanyan A, Guaragnella N, Trchounian K. · 2026-09-15
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.