Fumarate
Reactions involving Fumarate
Every recorded step where this molecule takes part
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Fumarate + H2O ⇌ L-malate
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produced Multiple pathway-specific catabolic enzymes Amino Acid Catabolism Overview (glucogeni… ST-0147
Glucogenic carbon skeleton → pyruvate or a gluconeogenic TCA-cycle intermediate
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Fumarylacetoacetate + H₂O → fumarate + acetoacetate
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Argininosuccinate → L-arginine + fumarate
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Succinate + FAD ⇌ fumarate + FADH2 (enzyme-bound); ubiquinone is reduced to ubiquinol in the respiratory chain
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Succinate + Q → fumarate + QH2
Showing all 6 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Amino Acid Catabolism Overview (glucogenic … | → | Citric Acid Cycle (TCA / Krebs Cycle) | cross-category |
| Electron Transport Chain (Complexes I–IV) | → | Citric Acid Cycle (TCA / Krebs Cycle) | within category |
| Urea Cycle | → | Citric Acid Cycle (TCA / Krebs Cycle) | cross-category |
Recent literature
Europe PMC · from cache · sorted by publication date
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1
Inhibition of Aryl hydrocarbon receptor Interleukin-22 signaling and worsening of intestinal inflammation by <i>Sutterella</i> species.
Dupraz L, Orianne G, Da Costa G, Gauthier R, Blondeau A, Boinet M, Farfar A, Creusot L, Magniez A, Dubois L, … · 2026-06-21
open access unreviewed -
2
Research progress of ferroptosis in gynecological diseases.
Chen W, Zhou W, Liu S. · 2026-06-19
open access unreviewed -
3
Fumarate dramatically enhances biocurrent output in Shewanella-based bioelectrochemical system.
Méhes G, Roy A, Gu S, Berggren M, Stavrinidou E, Simon DT. · 2026-05-17
unreviewed -
4
Deconfounded, quantitative microbiome profiling identifies robust multiple sclerosis markers and clinical covariate associations.
Pauwels A, Devolder L, Falony G, D'haeseleer M, Nagels G, Van Remoortel A, Derrien M, D'hooghe M, Raes J. · 2026-06-05
open access unreviewed -
5
Integrated transcriptome and metabolome reveal <i>Mycoplasma hyopneumoniae</i> -induced lipid accumulation, inflammation, oxidative stress, and energy imbalance in the liver of pigs.
Xue X, Bu Y, Yu C, Li J, Yang J, Gao M, Wang P, Gan Y, Zhang W, Fan S, Zhou R, Yin Z, Zheng X. · 2026-06-03
open access unreviewed -
6
Sulfide dynamics at the gut-microbiota interface: diet, oxygen and redox interplay.
Kumar R, Banerjee R. · 2026-06-02
open access unreviewed -
7
The plasma metabolome and clinical features of patients with coeliac disease in Northwest China.
Zhang W, Wu X, Li Y, Huang Z, Hui W, Shi T, Lu W, Bai H, Wu Q, Wang M, Liu K, Xu L, Gao F, Wu J. · 2026-05-16
open access unreviewed -
8
Impact of leucine-rich diet on placenta's proteomic and metabolomic profiles of pregnant tumor-bearing rats.
Dos Santos IF, Salgado CM, Carregari VC, Dos Santos RW, de Souza DM, Viana LR, Gomes-Marcondes MCC. · 2026-05-14
open access unreviewed -
9
Wubie Fanchun Formula-inducible metabolites in primary ovarian insufficiency model mice that facilitate ovarian renovation.
Chen Y, Chen S, Song B, Xia X, Zhang K, Chen L, Chi L, Wang Q. · 2026-05-12
open access unreviewed -
10
Host metabolism shapes the intestinal microbiota: a top-down paradigm of environmental selection pressure.
Ma Z, Shi H, Bai X, Wang Z, Cao J, Dong Y, Chen Y. · 2026-05-07
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.