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Junction / hub Pathway metabolite unreviewed

S-adenosylmethionine (SAM)

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Pathways
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Categories
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As substrate
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As product
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Reactions involving S-adenosylmethionine (SAM)

Every recorded step where this molecule takes part

All 6 Consumed 4 Produced 2

Showing all 6 reactions.

Pathway junctions through this molecule

Produced in one pathway, consumed in another

7 links
Produced in Consumed in Link
Methionine Cycle / Transmethylation (SAM Cy… → Catecholamine Synthesis within category
Methionine Cycle / Transmethylation (SAM Cy… → Phase II - Conjugation cross-category
Methionine Cycle / Transmethylation (SAM Cy… → Phospholipid Synthesis (Kennedy / CDP pathw… cross-category
Serotonin & Melatonin Synthesis → Catecholamine Synthesis within category
Serotonin & Melatonin Synthesis → Methionine Cycle / Transmethylation (SAM Cy… within category
Serotonin & Melatonin Synthesis → Phase II - Conjugation cross-category
Serotonin & Melatonin Synthesis → Phospholipid Synthesis (Kennedy / CDP pathw… cross-category

Recent literature

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Europe PMC · fetched just now · sorted by publication date

  1. 1
    Metabolic engineering of <i>Vibrio natriegens</i> for the efficient biosynthesis of ergothioneine from sucrose using non-sterile fed-batch fermentation.

    Liang X, Wang Y, Lv Y, Huang C, Huang Z, Wei J, Jiang S, Dong Z, Zhou Z, Lin M. · 2026-06-12

    open access unreviewed
  2. 2
    AMD1-mediated polyamine metabolism governs tubular repair fate by restraining senescence after kidney injury.

    Mao B, Zheng Z, Fu W, Cheng G, Wang L, Bao J, Liu X, Zhan H, Pan M, Liu J. · 2026-06-14

    open access unreviewed
  3. 3
    Significance of GSH and H<sub>2</sub>S regulation for cancer: an intricate interplay between diet, microbiota, metabolic reprogramming, and immune health.

    Majumder A, Majumder S, Bano S, Sen K, Nayak KB. · 2026-06-11

    open access unreviewed
  4. 4
    A prospective, randomized, double-blind, placebo-controlled, multicenter study of thiamin plus folic acid in the treatment of cognitive impairment in patients undergoing maintenance hemodialysis.

    Xie K, Jiang Y, Chen T, Liu S, Fang Y, Chen F, Shen J, Zeng X, Li P, Qiu T, Wang J, Yu L, Zang X, Wang N, Yua… · 2026-04-30

    open access unreviewed
  5. 5
    On the mode of anti-<i>C. albicans</i> activity of a bis(benzoxaborole) analogue of tavaborole.

    Gadakh S, Szczepińska T, Potoczna M, Okitsu-Sakurayama S, Podlasz P, Rogalska M, Kaczorowska E, Adamczyk-Woźn… · 2026-04-28

    open access unreviewed
  6. 6
    Engineering a heme-dependent tryptophan hydroxylase pathway in <i>E. coli</i> for enhanced melatonin production.

    Zhang L, Yin G, Pan S, Zheng X, Zhou S, Du G, Li J, Chen J, Xu R, Kang Z. · 2026-04-11

    open access unreviewed
  7. 7
    Functional identification of key enzymes in calycosin biosynthesis in <i>Astragalus membranaceus</i> and establishment of heterologous expression system.

    Cui MX, Hao Y, Li JN, Xu DD, Hao PX, Fu J, Lu Y, Li YT, Zhi LL, Zhang JZ, Lou HX, Cheng AX. · 2026-03-27

    open access unreviewed
  8. 8
    Microbiome signatures correlate with diet-mediated ADHD symptom reduction.

    Hontelez S, Guthrie M, Stobernack T, van Baarlen P, Rousseau C, Boks MP, Pereira RR, Boekhorst J, Kleerebezem… · 2026-04-16

    open access unreviewed
  9. 9
    Sulphur-containing amino acids promote the expression of <i>CG33474</i> and its neighbouring genes through the transsulphuration pathway.

    Xu L, Liu M, He L. · 2026-04-12

    open access unreviewed
  10. 10
    Epigenetic regulators polyphenols in neurodegenerative diseases: a promising intervention strategy.

    Li LH, Huang Y, Wang XX, Xu CC, Wu L, He KL, Han DX, Chang Z, Wang JQ, Ma RJ. · 2026-03-31

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.