Succinyl-CoA
Reactions involving Succinyl-CoA
Every recorded step where this molecule takes part
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consumed Succinyl-CoA:3-ketoacid CoA transferase (SCOT / OXCT1) Ketolysis (Ketone Body Utilization) ST-0088
Acetoacetate + succinyl-CoA → acetoacetyl-CoA + succinate
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consumed Mitochondrial ALA synthase (ALAS) Heme Biosynthesis (Porphyrin Pathway) ST-0177 rate-limiting
Glycine + succinyl-CoA → δ-aminolevulinate (ALA) + CO₂ + CoA
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consumed Succinyl-CoA synthetase (succinate thiokinase) Citric Acid Cycle (TCA / Krebs Cycle) ST-0273
Succinyl-CoA + GDP + Pi ⇌ succinate + GTP + CoA-SH
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produced Multiple pathway-specific catabolic enzymes Amino Acid Catabolism Overview (glucogeni… ST-0147
Glucogenic carbon skeleton → pyruvate or a gluconeogenic TCA-cycle intermediate
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L-Methylmalonyl-CoA -> succinyl-CoA
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Propionyl-CoA → succinyl-CoA
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Alpha-ketoglutarate + CoA-SH + NAD+ → succinyl-CoA + CO2 + NADH + H+
Showing all 7 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
High-level amyrin production in <i>Yarrowia lipolytica</i> via metabolic and enzyme engineering.
Elsharawy H, Abdullah CN, Yin X, Zhou J. · 2026-07-15
open access unreviewed -
2
Systematic enzyme and cofactor engineering for efficient ursolic acid biosynthesis in <i>Yarrowia lipolytica</i>.
Elsharawy H, He Q, Zeng W, Zhou J. · 2026-07-17
open access unreviewed -
3
Engineering nonconventional yeasts to produce carboxylic acids: Advances and Prospects.
Zhang L, Fan Y, Shi W, Zhou X. · 2026-07-16
open access unreviewed -
4
Ethanol exposure is associated with spatial and taxon-specific gut microbiota remodeling characterized by ecological adaptation rather than broad activation of microbial ethanol metabolism.
Li M, Mao J, Liu S, Yu H, Qin H, Liu X, Tu R, Chen S, Liu Z, Zhang S, Mao J. · 2026-09-25
open access unreviewed -
5
From planktonic to biofilm states: single-cell transcriptomics reveals metabolic reprogramming and cellular heterogeneity in <i>Acinetobacter baumannii</i>.
Li N, Hu Y, Liu L, Chen Z, Huang S, Li M, Mao X, Xue X. · 2026-08-21
open access unreviewed -
6
Live-attenuated <i>Toxoplasma gondii</i> RHΔ<i>ddx6</i> mutant establishes comprehensive immunity against acute, chronic, and congenital toxoplasmosis.
Yang Z, Wang J, Wu J, Fan Y, Ying T, Zhang H, Bai J, Wang Y, Liu P, Li G, Nie M, Tian X, Mei X, Zhang Z, Wang… · 2026-08-07
open access unreviewed -
7
Mechanistic pathways linking gut microbial metabolites, microbial structural products, and host-microbe co-metabolites to mitochondrial function.
Frye RE, Rossignol DA. · 2026-08-06
open access unreviewed -
8
Lactylation in influenza a virus infection: Current evidence, knowledge gaps, and future perspectives.
Yan YC, Li Z, He H, Wu M, Yang H, Wei F. · 2026-08-02
open access unreviewed -
9
Post-translational modification-regulating biomaterials for regeneration.
Abudousu A, Tang Y, Liu B, Xiang L, Wang Z, Li Y, Zhao D, Cui W. · 2026-07-18
open access unreviewed -
10
Branched-chain amino acids and gut microbiota: coregulation and impact on neurological function via the gut-brain axis.
Li Q, Fan B, Xiao Y, Zhang Z, Zhao S, Liao B, Zeng J, Shan X, Ye H, Wen Y, Zhang L, Guo H, Xiao F, Zhu H. · 2026-07-14
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.