Oxaloacetate

• produced Mitochondrial pyruvate carboxylase Gluconeogenesis ST-0016

  Pyruvate + HCO3− + ATP → oxaloacetate + ADP + Pi

• produced Cytosolic malate dehydrogenase Gluconeogenesis ST-0018

  Malate + NAD+ ↔ oxaloacetate + NADH + H+

• produced ATP-citrate lyase (ACLY) Fatty Acid Synthesis (De Novo Lipogenesis) ST-0061

  Citrate (cytosol) + ATP + CoA-SH → acetyl-CoA + oxaloacetate + ADP + Pi

• produced Multiple pathway-specific catabolic enzymes Amino Acid Catabolism Overview (glucogeni… ST-0147

  Glucogenic carbon skeleton → pyruvate or a gluconeogenic TCA-cycle intermediate

• produced Aspartate aminotransferase (AST / GOT) Transamination ST-0136

  L-aspartate + α-ketoglutarate ⇌ oxaloacetate + L-glutamate

• produced Malate dehydrogenase Citric Acid Cycle (TCA / Krebs Cycle) ST-0276

  L-Malate + NAD+ ⇌ oxaloacetate + NADH + H+

• produced Mitochondrial malate dehydrogenase (MDH2) Malate-Aspartate Shuttle ST-0355

  Malate + NAD+ -> oxaloacetate + NADH + H+ (matrix)

Showing all 7 reactions.