EC 2.4.2.8 HPRT1 2 reactions
Lesch-Nyhan syndrome: hyperuricaemia, self-mutilation, choreoathetosis, intellectual disability
Enzymes & cofactors
Search by name, gene symbol, EC number or the disorder it causes. Open any enzyme to see every reaction it catalyses, what accelerates it and what inhibits it.
Showing enzymes whose reactions use PRPP.
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EC 2.4.2.7 APRT 1 reactions
EC 2.4.2.14 PPAT 1 reactions
Committed step of purine synthesis; feedback-inhibited by AMP/GMP; azaserine site
EC 2.4.2.10 UMPS 1 reactions
Hereditary orotic aciduria: megaloblastic anaemia unresponsive to B12/folate; treat with uridine
EC 2.7.6.1 PRPS1 1 reactions
Showing all 5 enzymes.