EC 1.3.5.1 SDHA-D 1 reactions
SDH mutations: paraganglioma, phaeochromocytoma, GIST; inhibited by malonate
Search by name, gene symbol, EC number or the disorder it causes. Open any enzyme to see every reaction it catalyses, what accelerates it and what inhibits it.
SDH mutations: paraganglioma, phaeochromocytoma, GIST; inhibited by malonate
Inhibited by cyanide, carbon monoxide, azide, H2S
Homocystinuria: marfanoid habitus, DOWNWARD lens dislocation, thrombosis; B6-responsive forms
Erythropoietic protoporphyria; also inhibited by lead
Produces biliverdin, CO and Fe2+; rate-limiting for heme catabolism
SDH mutations: paraganglioma, phaeochromocytoma, GIST; inhibited by malonate
Showing all 9 enzymes.