Pathways

56 pathways across 7 categories. Open any one for its full ordered reaction list, regulation table and clinical notes.

Malate-Aspartate Shuttle

Energy Metabolism & Cellular Respiration Transport (redox) 5 steps

Cytosolic NADH Mitochondrial NADH (~2.5 …

Liver, kidney, heart

Open pathway

PW-033 unreviewed

Oxidative Phosphorylation (Chemiosmotic Mechanism and ATP Synthase)

Energy Metabolism & Cellular Respiration Catabolic (energy capture) 6 steps

Proton-motive force + ADP… ATP

Oxidative phosphorylation couples electron transport to ATP synthesis by the chemiosmotic mechanism: the respiratory chain creates an electrochemical proton gradient, and ATP synt…

Open pathway

PW-030 unreviewed

Pyruvate Dehydrogenase Complex (Link Reaction, connecting glycolysis to the TCA cycle)

Energy Metabolism & Cellular Respiration Catabolic (link) 5 steps

Pyruvate Acetyl-CoA + CO2 + NADH

The pyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA, thereby committing glycolytic carbon to mitochondrial oxidative metabol…

Open pathway

PW-049 unreviewed