56 pathways across 7 categories. Open any one for its full ordered reaction list, regulation table and clinical notes.
Triacylglycerol (TAG) synthesis esterifies three fatty acyl chains to glycerol, creating the principal long-term energy store in adipose tissue and a major export lipid in hepatic…
Open pathwayAmino-acid catabolism first removes or transfers nitrogen, then directs the carbon skeleton to a limited set of metabolic entry points. Glucogenic amino acids yield pyruvate or a …
Open pathwayAdrenal medulla, sympathetic neurons, CNS
Open pathwayAll cells; highest in liver and RBC
Open pathwayHeme biosynthesis forms protoporphyrin IX and inserts ferrous iron to generate heme, an essential prosthetic group for hemoglobin, myoglobin, cytochromes, catalases, peroxidases, …
Open pathwayHeme degradation disposes of heme released predominantly during turnover of senescent erythrocytes and converts its tetrapyrrole ring into bilirubin for biliary excretion. Macroph…
Open pathwayThe methionine cycle activates methionine to S-adenosylmethionine (SAM), the universal major methyl donor for DNA, RNA, protein, phospholipid, neurotransmitter, and small-molecule…
Open pathwayThe folate cycle uses tetrahydrofolate (THF) derivatives to carry and distribute one-carbon units at oxidation states ranging from methyl to formyl. These units support de novo pu…
Open pathwayNeurons, mast cells, endothelium
Open pathwayOxidative deamination releases the amino nitrogen of glutamate as ammonium while regenerating α-ketoglutarate. In the liver this provides mitochondrial ammonia for carbamoyl phosp…
Open pathwayLiver, most tissues
Open pathwayEnterochromaffin cells, CNS raphe nuclei, pineal
Open pathway