Junction / hub Pathway metabolite unreviewed
Acetoacetyl-CoA
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Pathways
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Categories
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As substrate
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As product
Reactions involving Acetoacetyl-CoA
Every recorded step where this molecule takes part
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Acetoacetyl-CoA + acetyl-CoA + H2O → HMG-CoA + CoA-SH
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Acetoacetyl-CoA + acetyl-CoA + H2O → 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) + CoA-SH
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consumed Mitochondrial thiolase (acetyl-CoA acetyltransferase, T2/ACAT1) Ketolysis (Ketone Body Utilization) ST-0089
Acetoacetyl-CoA + CoA-SH → 2 acetyl-CoA
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2 acetyl-CoA → acetoacetyl-CoA + CoA-SH
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2 acetyl-CoA → acetoacetyl-CoA + CoA-SH
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produced Succinyl-CoA:3-ketoacid CoA transferase (SCOT / OXCT1) Ketolysis (Ketone Body Utilization) ST-0088
Acetoacetate + succinyl-CoA → acetoacetyl-CoA + succinate
Showing all 6 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
6 links
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Cholesterol Biosynthesis (Mevalonate Pathwa… | → | Ketogenesis | within category |
| Cholesterol Biosynthesis (Mevalonate Pathwa… | → | Ketolysis (Ketone Body Utilization) | within category |
| Ketogenesis | → | Cholesterol Biosynthesis (Mevalonate Pathwa… | within category |
| Ketogenesis | → | Ketolysis (Ketone Body Utilization) | within category |
| Ketolysis (Ketone Body Utilization) | → | Cholesterol Biosynthesis (Mevalonate Pathwa… | within category |
| Ketolysis (Ketone Body Utilization) | → | Ketogenesis | within category |
Recent literature
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