382 reactions · fully sourced
Trace any molecule
through human metabolism.
Search pathways, follow a substrate to every product it can become, and see which enzyme runs each hop — with what speeds it up and what shuts it down.
Results for “Urea Cycle”
3 matches across four record types
0
Pathways
0
Reactions
0
Metabolites
0
Enzymes
0
Junctions
0
Disorders
Route finder
What can this molecule become?
Pick a source metabolite and walk every recorded reaction. Reversible steps go both ways, irreversible ones only forwards, and each hop names its enzyme.
Start tracing
Connectivity
See how pathways interlock
Shared metabolites drawn as edges between pathways.
Open mapBrowse by category
Every pathway grouped the way the source documents organise them
Hub metabolites
The busiest crossroads in the dataset
Rate-limiting steps
- Branched-chain alpha-ketoacid dehydrogenase complex (BCKDH) Amino Acid Catabolism Overview (glucogenic vs. ketogenic amino acids; brief overview of branched-chain amino acid catabolism and phenylalanine/tyrosine catabolism as representative examples)
- Phosphofructokinase-1 (PFK-1) Anaerobic Glycolysis / Lactic Acid Fermentation
- Carnitine palmitoyltransferase I (CPT-1) Beta-Oxidation of Fatty Acids
- Cholesterol 7-alpha-hydroxylase (CYP7A1) Bile Acid Synthesis
- Tyrosine hydroxylase (TH) Catecholamine Synthesis
- HMG-CoA reductase (HMGCR) Cholesterol Biosynthesis (Mevalonate Pathway)
- Isocitrate dehydrogenase (mitochondrial NAD+-dependent IDH3) Citric Acid Cycle (TCA / Krebs Cycle)
- Ribonucleotide reductase (RNR, class Ia) Deoxyribonucleotide Formation (Ribonucleotide Reductase pathway and thymidylate synthesis)