56 pathways across 7 categories. Open any one for its full ordered reaction list, regulation table and clinical notes.
Anaerobic glycolysis converts glucose to pyruvate and then reduces pyruvate to lactate, regenerating cytosolic NAD+ so glycolytic ATP production can continue when mitochondrial ox…
Open pathwayThe citric acid cycle (TCA cycle, Krebs cycle) oxidizes the acetyl group of acetyl-CoA to two molecules of CO2 while capturing reducing equivalents as NADH and FADH2 and generatin…
Open pathwayThe mitochondrial electron transport chain (ETC) transfers electrons from NADH and FADH2 to molecular oxygen through a sequence of redox carriers while using the released free ene…
Open pathwaySkeletal muscle, brown adipose tissue, brain
Open pathwayLiver, kidney, heart
Open pathwayOxidative phosphorylation couples electron transport to ATP synthesis by the chemiosmotic mechanism: the respiratory chain creates an electrochemical proton gradient, and ATP synt…
Open pathwayThe pyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA, thereby committing glycolytic carbon to mitochondrial oxidative metabol…
Open pathwayShowing all 7 pathways.