Enzymes & cofactors

Search by name, gene symbol, EC number or the disorder it causes. Open any enzyme to see every reaction it catalyses, what accelerates it and what inhibits it.

Enzymes Cofactor terms Vitamins & minerals

Cofactor / coenzyme

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Showing enzymes whose reactions use Mn2+. Remove

Enolase

EC 4.2.1.11 ENO1 / ENO2 / ENO3 3 reactions

Pyruvate kinase

EC 2.7.1.40 PKLR 2 reactions

PK deficiency: chronic non-spherocytic haemolytic anaemia

6-Phosphogluconate dehydrogenase

EC 1.1.1.44 PGD 1 reactions

Isocitrate dehydrogenase (mitochondrial NAD+-dependent IDH3) RL

EC 1.1.1.41 IDH3 1 reactions

Rate-limiting TCA step; IDH1/2 neomorphic mutations produce 2-hydroxyglutarate in glioma/AML

Phosphoenolpyruvate carboxykinase (PEPCK)

EC 4.1.1.32 PCK1 / PCK2 1 reactions

Showing all 5 enzymes.