Enzymes & cofactors

Search by name, gene symbol, EC number or the disorder it causes. Open any enzyme to see every reaction it catalyses, what accelerates it and what inhibits it.

Enzymes Cofactor terms Vitamins & minerals

Cofactor / coenzyme

Restrict to

Reset

Showing enzymes whose reactions use BH4. Remove

Nitric oxide synthase (nNOS/eNOS/iNOS)

EC 1.14.13.39 NOS1-3 1 reactions

NO -> cGMP; nitrate and PDE5-inhibitor axis

Phenylalanine hydroxylase (PAH) RL

EC 1.14.16.1 PAH 1 reactions

Phenylketonuria: musty odour, intellectual disability, hypopigmentation; BH4 defects cause malignant PKU

Tryptophan hydroxylase (TPH1/2) RL

EC 1.14.16.4 TPH1 / TPH2 1 reactions

Tyrosine hydroxylase (TH) RL

EC 1.14.16.2 TH 1 reactions

Rate-limiting for catecholamines; BH4-dependent

Showing all 4 enzymes.