rate-limiting unreviewed
Tryptophan hydroxylase (TPH1/2)
1 reactions · 1 pathways
Cofactors used
What it does, reaction by reaction
1 reactions
Serotonin & Melatonin Synthesis Amino Acid & Nitrogen Metabolism · Cytosol
step 1
Irreversible rate-limiting
L-Tryptophan + O2 + BH4 -> 5-hydroxytryptophan
Converts Tryptophan O2 BH4 into 5-Hydroxytryptophan
› Notes
Rate-limiting step.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
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