Glutathione (GSH)
Reactions involving Glutathione (GSH)
Every recorded step where this molecule takes part
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2 GSH + H2O2 -> GSSG + 2 H2O
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Xenobiotic/electrophile + GSH -> GS-conjugate -> mercapturic acid
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Electrophile + GSH -> GS-conjugate -> mercapturic acid
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LTA4 -> LTB4, or LTA4 + glutathione -> LTC4 -> LTD4 -> LTE4
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gamma-Glutamylcysteine + glycine + ATP -> glutathione (GSH) + ADP + Pi
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GSSG + NADPH + H+ -> 2 GSH + NADP+
Showing all 6 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Eicosanoid Synthesis | → | Glutathione Metabolism (gamma-Glutamyl Cycl… | cross-category |
| Eicosanoid Synthesis | → | Phase II - Conjugation | cross-category |
| Glutathione Metabolism (gamma-Glutamyl Cycl… | → | Phase II - Conjugation | cross-category |
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Engineered probiotics couple photothermal cuproptosis with biomechanical disruption and immune activation.
Zhang X, Liu X, Huang K, Jin B, Ma N, Liu H, Jiang H, Wang X. · 2026-09-21
open access unreviewed -
2
A transferrin receptor-targeted liposome for iron metabolism regulation-augmented photodynamic therapy in glioblastoma.
Wen R, He G, Wan Y, Guo X, Xiong S, Wu Y, Wei Y, Li D, Lin J, Huang P. · 2026-09-16
open access unreviewed -
3
Engineering bioactive citrate-based hydrogels for wound repair: From structure-function design to microenvironmental regulation.
Zhang L, Lei B, Zhao H. · 2026-09-08
open access unreviewed -
4
Functionalized biomaterial platforms for interventional embolization therapy of hepatocellular carcinoma.
Zheng N, Tang Z, Yang G, Deng L, Zhao Q, Zhao Y, Zhang J, Wang X, Chai Y, Chen Y, Wu Y, Fu Y, Liu S, Li J, Lu… · 2026-09-08
open access unreviewed -
5
Harnessing gasotransmitters for orthopaedic infection therapy: Mechanisms and advanced delivery platforms.
Zhang JY, Yang YQ, Zhang ZX, Jin JL, Luo ZY, Wang DY, Ruan CX, Dai TZ, Huang YL, Xu J, Shi JW, Li JY, Lei PF. · 2026-09-03
open access unreviewed -
6
Gas-propelled microneedles for precision transdermal therapeutics.
Xiao Z, Jia F, Wu W, Ieong H, Jiang Z, Peng S, Wu C, Wang W, Pan X, Huang Z. · 2026-09-03
open access unreviewed -
7
Quercetin-derived carbon dots-modified ZIF-8 and M2 macrophage-derived migrasomes-functionalized microenvironment-responsive nanocomposite hydrogel for osteoporotic bone defects regeneration.
Yin H, Li Y, Zhu Y, Yan Z, Han Y, Cheng F, Hu J, Ma J, Xing X, Yang C, Tian H, Chen W, Zhang Y. · 2026-08-30
open access unreviewed -
8
CodY constrains β-cypermethrin degradation by regulating physiological adaptation and soil ecological performance in <i>Bacillus cereus</i> GW-01.
Lei Y, Tang Y, Wei E, He M, Xu B, Liao Y, Li W, Wang Y, Wang Y, Wang S, Zhao J. · 2026-07-23
open access unreviewed -
9
Predictions and cross-center validation of IDH status and 1p/19q status in adult diffuse glioma with non-invasive magnetic resonance spectroscopy.
Tu Z, Hu W, Zhang J, Xing Z, Li J, Xu J, Lin M, Jiang X, Cao D, Zhang J, Guo D, Qu X. · 2026-06-01
open access unreviewed -
10
GSH-responsive nanoparticle drug delivery system for simultaneous blockade of CD73/A2AR to reverse adenosine-mediated immunosuppression.
Wang C, Gong Y, Zhang D, Huang C, Wang H, Chen P, Zhang H, Zhang H, Zhu J, Miao Z. · 2026-09-02
unreviewed
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