Glutathione (GSH)
Reactions involving Glutathione (GSH)
Every recorded step where this molecule takes part
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2 GSH + H2O2 -> GSSG + 2 H2O
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Xenobiotic/electrophile + GSH -> GS-conjugate -> mercapturic acid
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Electrophile + GSH -> GS-conjugate -> mercapturic acid
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LTA4 -> LTB4, or LTA4 + glutathione -> LTC4 -> LTD4 -> LTE4
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gamma-Glutamylcysteine + glycine + ATP -> glutathione (GSH) + ADP + Pi
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GSSG + NADPH + H+ -> 2 GSH + NADP+
Showing all 6 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Eicosanoid Synthesis | → | Glutathione Metabolism (gamma-Glutamyl Cycl… | cross-category |
| Eicosanoid Synthesis | → | Phase II - Conjugation | cross-category |
| Glutathione Metabolism (gamma-Glutamyl Cycl… | → | Phase II - Conjugation | cross-category |
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Evaluation of Desmidorchis adenensis for wound-healing: Targeting inflammation, redox balance, and FOXO1/MIP-2 signaling in a murine model.
Abdel-Sattar OE, El-Shiekh RA, Sabry MM, El-Halawany AM, Al-Hawshabi OSS, Salama A, Meselhy MR, Abdel-Sattar … · 2026-07-11
unreviewed -
2
Key molecular networks underlying retinol's biphasic effects on cell proliferation through multi-omics integrative analysis using genome-scale metabolic modeling.
He P, Xiang G, Yan Y, Zhong J, Liang Y, Shu P, Lu H. · 2026-06-19
unreviewed -
3
Targeted LC-MS/MS profiling highlights altered cerebrospinal fluid glutathione in cancer patients with CNS metastases.
Zhao X, Cui J, Wang Y, Wang Y, Zhang J, Li R, Kong D. · 2026-07-17
unreviewed -
4
A novel AIE + ESIPT mechanism-based fluorescent probe for selective detection and imaging of cysteine in living cells.
Kim D, Liu H, Kim YC, Churchill DG. · 2026-07-02
unreviewed -
5
Ethnopharmacological potential and mechanistic study of Platycodon grandiflorum stems and leaves and Lonicera japonica stems and leaves against acute lung injury.
Zhao N, Li H, Guo Y, Wu F, Wang X, Hua Y, Wei Y, Ji P, Ren J. · 2026-06-30
unreviewed -
6
Nanozymes: bridging nanoscale characteristics and catalytic mechanisms for advanced biomedical applications.
Sun Y, Yang Y, Kang X, Wang Y. · 2026-06-22
open access unreviewed -
7
Multifunctional nanozyme-phytochemical synergy induces immunogenic ferroptosis by disrupting the antioxidant defence system of tumour cells.
Zhao Y, Lu Y, Ma Y, Ru G, Feng W, Niu R, Liu Y. · 2026-06-17
unreviewed -
8
Research progress of ferroptosis in gynecological diseases.
Chen W, Zhou W, Liu S. · 2026-06-19
open access unreviewed -
9
Synergistic application of taurine and spermidine enhances wheat tolerance to neodymium stress through redox homeostasis, metabolic adjustment, and nutrient regulation.
Iqbal R, Mehmood H, Majeed A, Murtaza G, Rebouh NY, Alotaibi MS, Alotaibi SS, Ullah S, Huseynova A, Ali S. · 2026-06-15
open access unreviewed -
10
Shikonin suppresses diffuse large B-cell lymphoma progression by inducing ferritinophagy and ferroptosis <i>via</i> lncRNA ADPGK-AS1 downregulation.
Chen C, Chen X, Huang X, Xie Y, Shi P, Qian S, Chen Z. · 2026-06-15
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.