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MS
unreviewed

Glutathione synthetase (GSS)

1 reactions · 1 pathways

Cofactors used

What it does, reaction by reaction

1 reactions

Glutathione Metabolism (gamma-Glutamyl Cycle) Amino Acid & Nitrogen Metabolism · Cytosol

step 2 Irreversible/directional

gamma-Glutamylcysteine + glycine + ATP -> glutathione (GSH) + ADP + Pi

Converts gamma-Glutamylcysteine Glycine ATP into Glutathione (GSH) ADP Pi

Notes

Deficiency causes 5-oxoprolinuria (pyroglutamic aciduria) with haemolytic anaemia.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

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